78 research outputs found

    On Quasiperiodic Morphisms

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    Weakly and strongly quasiperiodic morphisms are tools introduced to study quasiperiodic words. Formally they map respectively at least one or any non-quasiperiodic word to a quasiperiodic word. Considering them both on finite and infinite words, we get four families of morphisms between which we study relations. We provide algorithms to decide whether a morphism is strongly quasiperiodic on finite words or on infinite words.Comment: 12 page

    Repetitions in infinite palindrome-rich words

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    Rich words are characterized by containing the maximum possible number of distinct palindromes. Several characteristic properties of rich words have been studied; yet the analysis of repetitions in rich words still involves some interesting open problems. We address lower bounds on the repetition threshold of infinite rich words over 2 and 3-letter alphabets, and construct a candidate infinite rich word over the alphabet ÎŁ2={0,1}\Sigma_2=\{0,1\} with a small critical exponent of 2+2/22+\sqrt{2}/2. This represents the first progress on an open problem of Vesti from 2017.Comment: 12 page

    A phase II study of docetaxel in patients with metastatic squamous cell carcinoma of the head and neck

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    This study was designed to evaluate the activity, safety and tolerance of docetaxel (D) in a selected population with metastatic squamous cell carcinoma of the head and neck (SCCHN). Twenty-four patients with no prior palliative therapy were enrolled and received D 100 mg m−2 by 1 h of infusion, every 3 weeks. All but two patients had been evaluated for efficacy on lung metastatic sites. No prophylactic administration of anti-emetics or growth factors was given. A pharmacokinetic study was performed in 22 patients. Twenty-one patients were assessable for response and 24 for toxicity. One hundred and four cycles were administered with a median of 4.5 (range 1–9) per patient. The median cumulative dose was 449 mg m−2. Partial responses were achieved in five patients with a median duration of 18.7 weeks (range 13.1–50.3). The overall response rate was 20.8% with a median duration of 11.0 weeks (range 2.4–52.6). The most frequent side-effect was neutropenia (79.2% grade IV) but with a short duration (median 4 days) and no febrile neutropenia. The incidence of moderate/severe fluid retention was 29.2% with one treatment discontinuation. Other toxicities (all grades) were common (skin 75%, asthenia 50%, infection 29.2%, nausea 16.7%, diarrhoea 12.5%, stomatitis 16.7%, vomiting 8.3% and HSR 8.3%). A mean clearance of 19.6 l h−1 m−2 and an area under the curve of 6.00 ÎŒg ml−1 h−1 was found in the pharmacokinetic analysis. Docetaxel is active in this selected population with metastatic SCCHN, with a good tolerance. © 1999 Cancer Research Campaig

    ABSTRACT

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    Methods from string and pattern matching have recently been applied to many problems in music retrieval. We consider the so-called lead sheet problem, where the harmony, melody, and, usually, bass line are presented separately. This is a common situation in some forms of popular music but is also significant for ”classical ” music in many cases. A number of different but related musical situations are analysed and efficient algorithms are presented for music retrieval in each one. 1

    A Linear Algorithm for the Detection of Evolutive Tandem Repeats

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    Evolutive tandem repeats using Hamming distance

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    Evolutive tandem repeats : a survey

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